Known for its memory boosting and stress-relieving effects, Phosphatidylserine is probably one of the best nootropic gifts from Mother Nature. However, with many supplement manufacturers looking to cash in on the biohacking buzzword, it’s not always easy to find a legit source of PS.
With that in mind, we decided to compile the following review of the top 10 best phosphatidylserine brands. Read on.
Top Phosphatidylserine Brands in 2023
Double Wood Supplements
In our view, the PS from Jarrow Formulas is underrated. It’s among the rare ones that are made from non-GMO sunflower lecithin.
Almost all other of its competitors are made from soy. Not that soy is an inferior ingredient or something. But if you’re looking to avoid soy, the Jarrow Formula PS is your best bet.
We indeed love its clean selection of ingredients. The product is free from fillers which means each soft gel contains nothing but the stuff you’re interested in.
What’s more? The company behind it, Jarrow Formulas, has an outstanding reputation. The company is based in Los Angeles and has been producing supplements since 1977.
With a reputation to keep, you can rest assured that they do a lot to ensure that their PS is professionally handled. That’s why we think that they deserve the number one spot on this review.
The PS from Natural BioScience doesn’t come cheap and it’s easy to see why. For starters, it’s made up of Sharp-PS which is a highly bioavailable ingredient.
You see, most cheap products contain generic PS. Only a small portion of Generic PS is absorbed in the digestive system. Most of it goes to waste (that’s why manufacturers of generic stuff provide it in extra-large capsules).
With Sharp-PS, though, all those issues are addressed. You get smaller capsules with an easy-to-absorb PS powder. So even though this product by NaturalBioScience is rated at 100mg, it’s for sure capable of punching above its weight.
And the best part is that it is soy-free. That’s because it’s obtained from Sunflower Lecithin and not soybeans.
In our view, this is a product we’d recommend to anyone willing to pay a premium for top-quality stuff. That said, its pills are made from gelatin meaning that it’s not vegetarian-friendly.
Other than that, it is made up of nothing but clean ingredients. So with each taken, you’re sure to get good value for your money.
Since the 90s, the Doctor’s Best brand has wowed us with its commitment to quality. And since it’s one of the companies that have been in this business for several decades, we believe they have the competency it takes to provide high-quality stuff.
Just like its competitor, this product contains a highly bioavailable form of PS instead of a generic one. Indeed, its 100mg of the active ingredient is from the patented SerinAid premium brand.
Premium ingredients are typically taken through extra refining to ensure they are of the highest quality possible. One benefit of this extra refining is that it ensures the pill size is smaller and easier to swallow which indeed is a benefit unique to the Doctor’s Best PS.
However, we have a few minor issues with this product. First off, the product is obtained from soybeans. So, if you have issues with those beans, you might want to avoid it.
Also, the product’s list of ingredients shows that it contains fillers. Among those is magnesium stearate which, though common, is viewed by some pundits as controversial. However, there are no claims so far to confirm anything bad about it.
Those issues notwithstanding, this stands out as a really good product. It’s contained in vegetarian capsules so it’s vegan-friendly.
Double Wood Supplements
The Double Wood Supplement is one of the best-known ones out there. The Philadelphia-based company behind this product is highly acclaimed all thanks to its vast experience in handling different kinds of natural nootropics.
By the time we compiled this review, their PS product had amassed more than 1,000 user reviews on Amazon. What’s more, 92% of those reviews were from satisfied users who rated it 4-stars and above.
There’s no doubt that this is a well-known brand. However, to understand the kind of value you get per bottle, we’d like to closely examine its list of ingredients.
First off, it contains 300mg of generic PS. That’s quite potent. The average PS compound out there contains 100mg of the active ingredients so evidently, this one contains 3X the standard dose (though generic).
Besides that, the product is among the most affordable ones we’ve reviewed so far. In fact, it goes of $0.16 per capsule which is cheaper than the average price of $0.27 on the markets currently.
But there is a catch. For you to get the 300mg serving, you’d need to take 2 capsules. So, essentially, the price per pill i.e. $0.16 represents 150mg potency.
Another issue with this product is that it’s encapsulated in gelatin pills. And that’s in addition to the fact that it’s obtained from soybeans.
Are you tired of taking phosphatidylserine capsules that don’t seem to work at all? It’s time to tap into the triple power found in this product from Swanson.
One thing that attracted us to this product is that it contains 300mg of Sharp PS. Yup, you read that right. This is so far the only product we’ve come across that contains such a potent dosage of a premium-grade, highly bioavailable ingredient.
As a trade-off, it doesn’t come cheap. You’d need to fork out $0.70 per capsule which is almost 3 times higher than the average price of $0.27 seen so far.
To make up for that, the company provides free shipping for all orders made from the US of A.
We’d also like to note that this product is quite well packaged and presented. The pills are also quite easy to swallow.
On the flip side, though, the product contains soy along with other fillers which we’re ashamed to see on the list considering the price this product retails at. They include Silicon dioxide and a bunch of antioxidants.
We also noticed that the product is encapsulated in gelatin soft gels.
Bottom line – this is a great product but it’s far from perfect. We’d only recommend it for anyone who is after enhanced potency but if you’re looking for a simple product that does its job, you might want to go for a cheaper product instead.
Since 1968, Now Foods has grown to become one of the top-tier supplement makers in the US of A. Indeed, it’s a company that has weathered all kinds of challenges. We think that the company’s secret to survival is in playing it safe when formulating their ingredients.
You won’t find them going out of their way to create the most potent products available. Plus, they seem to only target newcomers to the biohacking world.
Their PS contains 100mg of the active ingredient (generic). Plus, the company has provided a choline donor to add even more value to the product.
At its price, of $0.26 per serving, we feel that this product is quite reasonably priced. And to make the deal even sweeter, it’s contained in vegan capsules.
On the flip side, though, we could easily point out quite a few fillers in it among them Silica and Magnesium stearate.
If you have a top-dollar to spare in exchange for a well-made and packaged product, the PS from Solgar might be worth checking out.
First off, unlike any other supplements we’ve reviewed so far in this article, it’s packaged in a glass bottle. It, therefore, comes in handy if you’re looking to minimize your exposure to plastics especially with issues related to BPA being a top concern these days.
Besides that, this product is made up of top-quality PS which is obtained from 1000mg of soy lecithin. This extra processing boosts its potency ensuring lots of it is put to optimal use.
However, you should note that this product is obtained from soy lecithin and obviously contains soy.
There’s one thing we’d like to give the Source Natural team credit for. That is their ability to push barriers and create products that go above and beyond expectations.
For instance, their PS supplement is made up of 500mg Sharp PS along with an extra 100mg of generic PS. This seems like a formula that’s meant to leave zero-chances of complaints.
However, all that PS might prove too much if you’re a first-timer. So, once again, this is a good product only that its potency might be a little too much for newbies.
The unique thing about Phosphatidylserine from Thorne is that it contains the manufacturer’s patented Iso-Phos ingredient.
So, what’s Iso-Phos? You might be wondering. Well, all we can confirm this far is that it’s a highly bioavailable form of the active ingredient which is designed to ensure you get the most from each pill.
At 100mg per serving, we’d recommend this product to beginners. Advanced biohackers would be better off taking at least 2 pills of it per day.
However, at its price of $1 per capsule, we feel that this product is grossly overpriced.
Save for its ridiculous price tag, this is a product to die for. First off, it contains a natural derivative of PS with absolutely no lab handling.
So, if you’re worried that extra lab handling (e.g. one meant to increase potency) can damage the integrity of your PS, Pure Encapsulations are your go-to guys.
Their generic PS is rated at 100mg per pill. What’s more? Each pill measures at well below 1 inch meaning they’re quite easy to swallow.
We scanned through this product’s list of ingredients several times and we couldn’t find any fillers in it. Yup, you read that right.
In a nutshell, this is a simple product made up of nothing but clean ingredients. Only that at $1.08 per pill, it’s almost 4 times as expensive as the average product reviewed so far in this write-up.
Of course, this is by no means an exhaustive list of all the Phosphatidylserine supplements available out there. We’re, however, confident that all the brands on this list made it here purely on merit. So, feel free to narrow down your research to the 10 alternatives above.