Top 10 Best Lion’s Mane Supplements & Brands

Lion’s Mane is a type of mushroom believed to improve mental clarity, build memory, and boost focus. And even though more scientific evidence might be needed to support some of those claims, the consensus is that these shrooms can be of benefit if taken in the right way. Today, we’d like to talk about a few of the best ready-made lion’s mane supplements to compare their effects.

Top Lion's Mane Mushroom Brands in 2024

Brands

Price

Rating


Four Sigmatic

$$

Nootropics Depot

$$

Double Wood

$

Genius Mushrooms

$

Brain Forza

$$

Host Defense

$$

Dr.Emil Nutrition

$$

Purest Vantage

$

Real Mushrooms

$$

Toniiq

$

1

Four Sigmatic

foursigmatic mushroom coffee e1574303289491

This brand of Lion’s Mane has generally been well received by users who laud it for its calming effects. The product is mildly caffeinated which makes it a gentle stimulant. What’s more, it contains Lion’s Mane which is believed to fuel creativity.


We’d recommend it for folks who enjoy black coffee and mushrooms. Unlike concentrated coffee, this beverage lacks the bitterness you’d typically get by intensifying your coffee cup.


Other than that, this is a great, mild and safe product (mildly spicy). It does not come cheap but has just the right ingredients to justify the price.

Pros

  • Great packaging
  • Awesome product quality
  • Effective
  • Easy to use

Cons

  • Pricey
  • Some don’t like its taste

2

Nootropics Depot

nootropics depot lions mane

One thing we like about the Nootropics Depot Lion’s Mane is that you know exactly how much of the active ingredient is in each pill. That’s because the company doesn’t hide anything in proprietary blends.


That’s a really good thing if you’re looking for transparency.


Simply put, the USDA Organic certified product contains 500mg per serving which is potent but not over-the-top. Unlike its competitor from Four Sigmatic, this one only features one, clean ingredient.


A potential downside with it is that we’ve come across a few people complaining that this made them anxious. So, if you have anxiety issues, you might want to stack it with Ashwagandha or avoid it altogether.

Pros

  • Clean ingredients
  • 3rd party tested
  • Reasonably priced

Cons

  • Paradoxical effects reported

3

Double Wood Supplements

double wood lions mane

Are you one of those who complain of feeling nothing after taking lion’s mane mushroom? You might want to give these 1000mg capsules a shot.


The product is made right here in the US (Philadelphia) plus is certified as non-GMO and gluten-free.


But if you’re drawn to taste and good smell, this might not be the ideal supplement for you. It’s tasteless and has a faint lobster-like flavor.


Another thing, this is one of the supplements whose effects aren’t always subtle. Some people have to take it for several months to notice its benefits.

Pros

  • Highly potent ingredients
  • Vegetarian-friendly, non-GMO formula
  • Easy-to-swallow capsules

Cons

  • Plain-tasting formula

4

Genius Mushroom

genius mushrooms

What you get here is a combination of Cordyceps, Reishi, and Lion’s Mane all combined in equal measure i.e. 500mg. The powder is then packaged in veggie capsules made from Hypromellose.


You simply need to take 3 capsules of this every day. The manufacturer claims that this product can relax, rejuvenate and promote calmness.


However, like all the other top lion’s mane supplements reviewed above, this one isn’t perfect. It’s important to remember that this is a gentle and slow-acting powder. So, you need to take it for a couple of months to witness any major changes in your way of thinking and how you do things.

Pros

  • Well packaged
  • There’s a discount if you subscribe
  • May improve mental clarity
  • Contains clean, earth-grown nutrients

Cons

  • No immediate difference in energy levels
  • May cause bloating

5

Brain Forza

Brain Forza is a relatively popular supplement brand and it’s easy to see why. Their ingredients are certified organic. Plus, unlike the competition, the company claims to use the whole fruiting.


Another good thing with this product is that it’s made from lab-grown mushrooms. These are shrooms grown in controlled environments away from the risks of toxic soils.


We think this is a great product although it may take several days if not weeks to feel its effects.

Pros

  • Quality ingredients
  • Great packaging
  • Fast shipping

Cons

  • Lab-grown mushroom may lack some of the elements found in wild shrooms

6

Host Defense

host defense lions mane

This is a brand that’s closely associated with Paul Stamets. Paul is a renowned mycologist and entrepreneur who is known for advocating for medicinal fungi.


What you get in the pills are 550mg of Lion’s Mane combined with myceliated brown rice. Now, that’s perfectly fine if all you’re looking for is a simple supplement. However, if you’re choosy and looking for a product that’s made from the whole fruiting of the mushroom’s body, this might not stun you.


Segue, the product seems well-packaged. It’s tasteless, though. So, if you’re used to flavored supplements, it’s important to set your expectations right before going for this one.

Pros

  • Associated with a leading mycologist
  • May help with brain fog
  • Great packaging, shipping & delivery
  • Some claim that they could feel its effects within a few days of use

Cons

  • Cheaper, more powerful options exist

7

Dr. Emil Nutrition

dremil nutrition lions mane

With the recommended dosage for this nootropic being 500mg to 3000 mg per day, supplement manufacturers have quite some room to flex their muscles. And so far, this brand of Lion’s Mane from Dr. Emil Nutrition is the most powerful one we’ve come across as it packs 2100mg of the active ingredient.


The product may help in the management of depressive symptoms plus it might also make your brain clearer.


So, if you’ve been battling mental fog, it might help. However, it probably won’t make you any smarter.

Pros

  • Potent lion’s mane
  • Well-packaged
  • Organic shrooms used

Cons

  • Pricey
  • Different colored pills when you reorder

8

Purest Vantage

purest vantage lions mane

If you’re looking for a product that’s certified as free from additives, this one from Purest Vantage would be a perfect fit. It’s made in an FDA inspected facility and in accordance with the GMP guidelines.


What we like even more about it is the fact that it packs 1800mg of the active ingredient. That’s one of the highest potency we’ve encountered in this review so far.


On the flip side, though, the product isn’t as well-known out there. So, there are fewer people talking about it than its competitors.

Pros

  • Well-packaged
  • Potentially powerful
  • Clean ingredients
  • Made in FDA accredited facility

Cons

  • A detailed supplement’s facts sheet would help people understand it better
  • Not popular

9

Real Mushrooms

real mushrooms lions mane

With only 2 capsules of this mushroom powder, you’ll be well on your way to giving Albert Einstein a run for his money. Well, at least that’s what the manufacturer would like to have all of us believe.


For now, all we can confirm is that the product packs 1000mg of the active ingredient. That’s relatively high and safe.


The only issue is that it’s made in Canada and we can’t verify where the company gets its ingredients from.

Pros

  • Potent ingredients
  • USDA-Organic certified
  • 3rd party tested

Cons

  • Expensive

10

Toniiq

toniiq lions mane 2 e1574304314391

From where we stand, this is a product that has received both love and hate from its users. There are those who swear by its effects as well as a few who think it’s overrated.


Our verdict is that this is a relatively well-made dietary extract. However, the way it's marketed might make you believe that it will give you some quick wins – and that’s far from the truth.


Like any other Lion’s Mane extract, this one tends to be slow off the blocks with effects building up over time.

Pros

  • Great packaging
  • Easy-to-swallow pills
  • Made in USA
  • Organic, non-GMO and gluten-free

Cons

  • Sensational marketing
  • Some users complained of the pills having a “burnt-electronic-like” taste

Final Thoughts

This is by no means an exhaustive list of the top-rated lion's mane mushroom supplements. However, we believe that the 10 alternatives mentioned-above represent some of the finest options available out there currently.