Overall Rating


Mitogen is sold as a complementary supplement to the Nexus Aniracetam stack. While the latter is meant to work almost immediately, the former is a bit slower off the blocks as it is meant to support energy production at the mitochondrial level.

The stack is loaded with vitamins, antioxidants, and BioPQQ which is a premium version of the generic Pyrroloquinoline Quinone nootropic compound.

So, the bad news is that you might not feel anything after immediately after taking this supplement on its own (which is probably why the company recommends buying it alongside Nexus). The good news is that its effects kick in in the long-run and include a reduction in the rate of cognitive decline.

Product Overview

Most nootropics focus on improving the neurotransmitter balance in your brain but they don’t address one thing – the mitochondria. Mitochondria are the organelles in your cells responsible for the production of energy.

Without properly functioning mitochondria, you would struggle to get anything done even after taking the best stimulants available.

This is the loophole Mitogen seeks to seal. It provides your cells with the building blocks for new mitochondria.

On top of that, this supplement has the potential to promote NGF synthesis which is important for the survival of neurons.

In the long-run, this has the potential to boost your physical energy.

About the Manufacturer

This supplement is formulated by Axon Labs LLC which runs a cGMP manufacturing facility. They’re based right here in the US – Corvallis, Oregon to be precise.

List of Ingredients

Unlike its sibling Nexus which contains Aniracetam, Mitogen contains a bunch of vitamins, PQQ along with sulbutiamine i.e. a lab-made ingredient. Were it not for sulbutiamine (and Idebenone), Mitogen would have been an all-natural supplement.

1. Vitamin C – 500mg

Also known as ascorbic acid, Vitamin C is known to be in high concentrations within the hippocampus. The hippocampus is the part of the brain responsible for memory. Therefore, by replenishing its supplies, Mitogen seeks to support your brain’s storage capacity.

On top of that, this vitamin plays an important role in the conversion of norepinephrine from dopamine. This can lead to mild feel-good effects.

2. Vitamin B5 – 500mg

Vitamin B5 is also known as pantothenic acid. It’s needed for normal brain function and fat metabolism. It plays a role almost similar to the one accomplished by Phosphatidylserine (PS) which helps in the production of healthy fats used in the formation of healthier brain cells.

3. Mitochondrial Energy Blend – 660mg

This is a proprietary blend that brings together Sulbultiamine, Idebenone, BioPQQ, and R-Lipoic Acid. However, it’s not clear how much of each ingredient has been used in this blend.

  • Sulbutiamine - Originally formulated in France, Sulbutiamine is a fat-soluble nootropic compound meant to reduce fatigue. On top of that, it packs antioxidant properties meaning that it has what it takes to help your body get rid of toxins. One of the long-term effects of taking it is that it can improve your muscular strength. This way, it can leave you physically stronger.
  • Idebenone - Idebenone is a lab-made version of Coenzyme Q10. As you might be aware, CoQ10 works perfectly alongside PQQ in memory and strength building. And that’s probably why the good guys at Axon Labs found it important to include Idebenone into the list of Mitogen ingredients.
  • R-Lipoic Acid - R-Lipoic acid is a natural compound that is known as an important cofactor in mitochondrial multi-enzyme functions. It is an essential catalyst in biological activities leading to the production of energy at the cellular level. Besides that, it plays a pivotal role in aerobic metabolism. That’s why it’s commonly found in bodybuilding supplements.
  • BioPQQ - This is a highly bioavailable form of PQQ. And as we have already stated it plays a major role in the production of new mitochondria. A long-term effect of taking this natural nootropic is that it boosts your energy supply but without causing the jitters typically caused by stimulants.

Mitogen By Axon Labs

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How to Take It

You’re supposed to take 2 to 3 capsules of this supplement in the morning. You should, however, avoid taking more than 3 capsules per day. You may need to consult your medical doctor if on other medically prescribed treatment before taking this.

What We Like About This Stack

  • Long-term approach to energy generation
  • No jitters
  • Can prevent cognitive decline
  • Supports long-term health benefits
  • Great customer support

What We Don’t Like

  • It contains Idebenone which is a drug, lab-made version of COQ10
  • No immediate from taking it
  • Uses proprietary blend

Final Thoughts

Mitogen seems like a good health supplement. However, we’d recommend taking it along with any other that contains fast-acting ingredients if you’re looking for immediate results.

The fact that it contains Idenone instead of COQ10 makes it less desirable to anyone who wants to cut down on the consumption of lab-made ingredients. Otherwise, this is a pharmaceutical-grade ingredient and you shouldn’t have any major issues taking it unless your doctor recommends otherwise.

Verdict: Good supplement but only if taken as a complementary supplement.